Thursday, June 9, 2011

Welcome to the Beginning of the End of the PC Era

Welcome to the Beginning of the End of the PC Era

Tech pundits have a bizarre habit of declaring products dead long before they're actually goners. (Here, for instance, is an article that says Facebook is toast — from 2008.) Me, I do my darndest to resist the temptation to play premature coroner. I will say this, though: if the PC does end up mortally wounded someday, we may look back at early June of 2011 as the moment when its death warrant was signed.

In the past eight days, Microsoft and Apple have shown off upcoming versions of their operating systems. Their plans differ in fundamental respects, but both companies are looking past the PC era we've lived in for the past three decades. They're building software for an age in which people do their computing and communicating on all kinds of gadgets — ones that are simpler, more portable and more Internet-centric than PCs as we've known them. (See a consumer wish list for Windows 8.)

First, the Microsoft news. At the Wall Street Journal's D9 conference in Rancho Palos Verdes, Calif., last week, Windows honcho Steven Sinofsky presided over the first public demo of Windows 7's successor, which for now is going by the sensible code name Windows 8. (Microsoft posted a similar preview as an online video.)

The demo showed only one aspect of Windows 8, but it was a lulu. Windows is getting its most dramatic makeover since at least Windows 95, with an all-new interface that looks a lot more like Windows Phone 7 rather than anything that currently runs on a desktop PC or laptop. It's clever, colorful and designed to be navigated with fingers rather than a keyboard and mouse, showing plenty of iPhone/iPad influence without being a mere knockoff.

The old-school Windows interface isn't gone; existing software will still run. But Microsoft is prepping for a transition similar to the migration from DOS to Windows that happened a couple of decades ago. It may take a while to complete, but it's under way.

Coming to any definitive conclusions about Windows 8 on the basis of last week's demos would be like reviewing a movie on the basis of a teaser trailer that came out a year and a half before the film. (Microsoft isn't saying when the software will ship, but mid- to late 2012 is a good bet.) The sneak peek was enough to leave me asking a lot of questions, though:

Will Windows 8's dual interface feel like the best of both worlds rather than a disjointed mess? Making it make sense will be a massive challenge. (I'm keeping an open mind until I get some hands-on time.)

See TIME's Pictures of the Week.

See the Cartoons of the Week.

What sort of computers will run it best? I suspect that Microsoft has iPad-style tablets and all-in-one PCs akin to HP's TouchSmarts in mind. But Windows 8 will also need to run well on hundreds of millions of garden-variety computers. (Watch TIME's video "Windows Phone 7 Tips and Tricks.")

How will software evolve to reflect the new interface? Popular apps such as e-mail and spreadsheets will need more than a minor rethinking to go touch-only. And without a critical mass of software tailored to take advantage of Windows 8's new features, there will be no reason to make the upgrade.

Windows users are such a conservative bunch that 10-year-old Windows XP remains the world's favorite operating system. Will they be willing to take a giant step into the post-PC age? We'll see!

That Microsoft didn't share any details on these and other major issues doesn't mean it doesn't have coherent answers. It might just be waiting to spill the beans until September, when it will release more information about Windows 8 — and probably a preview version — at a developer conference called Build.

As for Apple, Steve Jobs and friends spent a couple of densely packed hours on the morning of June 6 at its WWDC conference in San Francisco walking through the next versions of OS X (the operating system used by Macs) and iOS (the one that powers the iPhone, iPod Touch and iPad), as well as a new Internet service called iCloud. Scarcity of information wasn't a problem: if anything, the company unloaded so much new stuff that figuring it all out is going to take a while. (OS X 10.7 Lion is scheduled to arrive in July; iOS 5 and most of iCloud are due "this fall.")

The part of the Appleverse that's changing the least is the one most directly comparable to Windows: OS X. Its WWDC preview was mostly a recap of an event Apple held last October and focused on tweaks that make the operating system feel a bit more like its glamorous young cousin, iOS, without scrapping the existing interface. (Apple says it has no plans to make touchscreen Macs.) Lion will make better use of Apple's oversize touchpads, letting you supplement keyboard input with gestures to perform tasks like bopping between programs. It will get Launchpad, an optional home for your apps that mimics the iPhone and iPad home screens. And the Mac App Store that opened for business in January will be built right into the operating system.

Lion mostly looks like an appealing traditional software upgrade, not a departure — and a deal at just $29 for a copy that can be installed on all the Macs associated with one Apple ID. For the first time, Apple is distributing an OS X upgrade as a download through its Mac App Store; no DVD will be required (or even available).

iOS, on the other hand, is going to change in ways that may shift the tectonic plates of the computing world at least a teensy bit. For one thing, it's gaining autonomy. For the first time, you'll be able to use an iPhone or iPad without ever connecting it to a Mac or Windows PC with an archaic old USB cable — or, for that matter, owning a Mac or Windows PC at all. It's also getting a bunch of meaty new features, such as a revised notification system, a more desktop-like Safari browser and the ability to search the contents of all your e-mail.

Just as Microsoft probably won't use the term "post-PC" when describing Windows 8, Apple isn't going to describe iOS 5 as a PC operating system. In a real sense, however, that's what it's trying to be: a software platform so comprehensive and self-contained that it won't have to play second fiddle to anything else. Nobody reading this article is going to scrap his or her PC for an iPad-style tablet in the near future, but the day is going to arrive when that won't be a wacky notion — and this upgrade will help Apple get there.

And then there's iCloud. I said earlier that it's an Internet service, but that's oversimplifying matters. It's really a suite of services for storing and shuttling information of all sorts among iPhones, iPod Touches, iPads, Macs or Windows PCs, including e-mail, calendars, contacts, documents, presentations, photos, music you bought from Apple, music you acquired elsewhere, apps and more. It'll replace the company's MobileMe service and act rather like an Internet-based version of iTunes. It's all very, very ambitious. Much of iCloud will be free, but you'll pay for some options, like cloud-based storage space exceeding 5 GB — and, of course, for music and movies, paid apps and other content.

iCloud has the potential to evolve into a replacement for one of the PC's defining components: a local hard disk with vast amounts of data stored on it. I suspect Apple is already looking forward to the day when it can eliminate hard disks across the Mac line, much as the original iMac did away with the floppy drive back in the late 1990s.

But even if you're not the type to bristle at the notion of depositing massive amounts of your data on Apple servers in North Carolina, you may be cautious about assuming that an offering with so many moving parts will, in Jobs' oft-repeated words, "just work." Jobs admitted as much at WWDC when he brought up the less ambitious, occasionally erratic MobileMe and didn't deny its shortcomings. The only way to render a meaningful verdict on iCloud is to wait until it's available, use it, and see if it does, indeed, just work.

Microsoft's Windows 8 news — so far — is about one overwhelming change: the new interface. Lion, iOS 5 and iCloud are about a jillion small ones that aren't a huge whoop on an individual basis. Most of them feel familiar, in fact: they already exist in third-party iOS apps or on competing platforms like Android. Apple's core competency isn't doing unprecedented things; it's doing existing things better than other companies, doing them itself on its own terms and stitching them together as seamlessly as possible. With its new software and services, it aims to do more of that seamless stitching than ever before.

Did I mention that Apple and Google aren't the only tech behemoths trying to figure out what comes after traditional PCs? Google is also in the game with upcoming Chromebooks based on its Chrome OS. They're basically minimalist laptops that run only a Web browser — and they provide a third distinct vision of the post-PC device.

Even with all this change in the air, preparing a eulogy for traditional PCs is silly: It's going to be many, many years before the last one is powered down for the final time. But while technologies rarely die, they frequently shuffle off into semiretirement to make way for new ways of doing things. We already knew that Apple and Google were eager to see classic PCs start to make way for upstart devices; now it's clear that Microsoft is also preparing itself for that eventuality. It's going to be fascinating to watch them duke it out — and to see how consumers, who ultimately call the shots, respond.

Source

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Commentary

This article is ridiculous in a number of ways.

1. First lets talk about the PC gaming sector of the market. Forget the fact that tablets currently lack any power or performance/ proper Hard Drive space, and forgetting the fact that it'll take at least a decade to get there, there is no way to play games properly on a tablet.

Unless the tablet has a mouse and keyboard input and has a big screen, most games can't be played with just touch screen. If a tablet has both of these inputs it's ESSENTIALLY a PC, just shrunken down.

2. Also how do you type a long essay at 50 words per minute on a tablet, without a keyboard?

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Regardless of the technological differences right now, the main thing holding tablets back is the medium. Touch screen is very limited in functionality.

PC's can never die because the mouse and keyboard are irreplaceable.

Touch screens can not compete with it and as long as a mouse and keyboard connect to a screen, you basically have a PC.

PC's are here to stay for a few decades minimum. The only thing to possibly surpass them would be proper voice recognition and virtual reality.

Those are decades away. We haven't even gotten augmented reality setup yet.

Wednesday, June 8, 2011

Drug makes hearts repair themselves

Drug makes hearts repair themselves

Man having heart attack More people are surviving heart attacks, but that means more are living with heart failure

Related Stories

A drug that makes hearts repair themselves has been used in research on mice.

The damage caused by a heart attack had previously been considered permanent.

But a study in the journal Nature showed the drug, thymosin beta 4, if used in advance of a heart attack, was able to "prime" the heart for repair.

The British Heart Foundation described repair as the "holy grail of heart research", but said any treatment in humans was years away.

Due to advances in health care the number of people dying from coronary heart disease is falling.

But those living with heart failure are on the rise - more than 750,000 people have the condition in the UK alone.

Wake up

The researchers at University College London looked at a group of cells which are able to transform into different types of heart tissue in an embryo.

UK Heart statistics

Deaths from coronary heart disease

  • 1961 - 165,216
  • 2001 - 117,743
  • 2009 - 80,223

Estimated people living with heart failure

  • 1961 - 100,000
  • 1971 - 300,000
  • 2010 - 750,000

Source: British Heart Foundation

In adults epicardium-derived progenitor cells line the heart, but have become dormant.

Scientists used a chemical, thymosin beta 4, to "wake them up".

Professor Paul Riley, from the University College London, said: "The adult epicardial cells which line the muscle of the heart can be activated, move inward and give rise to new heart muscle."

"We saw an improvement in the ejection fraction, in the ability of the heart to pump out blood, of 25%."

As well as pumping more blood, the scar tissue was reduced and the walls of the heart became thicker.

Peter Weissberg, medical director of the British Heart Foundation, said he was "very excited" about the research but warned the scale of improvement seen in animals was rarely seen in humans.

Heart Epicardium derived progenitor cells (in red) lining the heart

However, he argued that even a small improvement would have a dramatic impact on people's quality of life.

"A normal heart has lots of spare capacity. In patients with heart failure it is working flat out just to sit down [and] it's like running a marathon," he said.

"You could turn a patient from somebody who's gasping while sitting in a chair to somebody who can sit comfortably in a chair."

Advance therapy

The mice needed to take the drug in advance of a heart attack in order for it to be effective. As the researchers put it, "the priming effect is key".

If a similar drug could be found to be effective in humans, then the researchers believe it would need to be prescribed in a similar way to statins.

Professor Riley said "I could envisage a patient known to be at risk of a heart attack - either because of family history or warning signs spotted by their GP - taking an oral tablet, which would prime their heart so that if they had a heart attack the damage could be repaired."

He said this could be available in 10 years.

The British Heart Foundation, which funded the study, said repairing a damaged heart was the "holy grail" of heart research.

The results strengthened the evidence that drugs could be used to prevent the onset of heart failure, it said.

Source